FAQs

How is Bead Block® packaged?

  • Bead Block® is presented in a 20ml syringe
  • Each syringe is presented in a sterile, sealed pre-formed Tyvek® peel-away tray with a label colored to denote the specific size range
  • Each syringe contains approximately 2ml of Bead Block® in non-pyrogenic, sterile, physiological buffered saline
  • Each syringe is intended for single patient use only
  • The syringe should not be re-sterilized and any unused material should be discarded

 What size range of Bead Block® is available?

Bead Block is available in five sizes from 100µm to 1200µm

 
Bead Block® sizes
Label Color Nominal Bead size Volume of beads
Yellow 100-300µm 2ml
Blue 300-500µm 2ml
Red 500-700µm 2ml
Green 700-900µm 2ml
Purple 900-1200µm 2ml

What are the indications for Bead Block®?

Bead Block® is a 510K cleared embolic agent intended for the purpose of embolizing the blood vessels of a variety of hypervascularized tumors and arteriovenous malformations.

How many beads are there per syringe of Bead Block®?

When using Bead Block®, the volume of embolic required to reach the desired end point is the critical factor

The number of individual beads is not usually considered when deciding the volume to deliver to the patient 

 
Bead Block®
  100-300µm 300-500µm 500-700µm 700-900µm 900-1200µm
Approximate number
of beads in 2ml
Bead Block® syringe*
200,000 40,000 10,000 4,000 2,500
* Theoretical calculation based on the average diameters of a normal distribution of beads in a vial. BTG data on file
 

What is Bead Block® tinted with?

Bead Block® is tinted with a dye called Reactive Blue 4 (CI 61205). This dye has many names such as:
  • Procion Blue MR
  • Reactive Brilliant Blue
  • Reactive Blue MR
Reactive Blue 4 (CI 61205) has been used in many applications and is routinely used for the tinting of contact lenses.

What is the preparation and administration protocol for Bead Block®?

  1. Draw up contract medium directly into the Bead Block® pre-filled syringe. If Bead Block® sinks, add more contracts. If Bead Block® floats, add more saline.
  2. Remove all air from syringe.
  3. Gently invert the 20ml syringe several times to evenly suspend the Bead Block® contrast solution.
  4. Do not use a shaking motion.
  5. Wait to allow Bead Block® to suspend properly.

Procedure Prep 1Procedure Prep 2

What type of contrast should I add to Bead Block®? How much should I use?

  • Always use a non-ionic contrast medium
  • The quality of contrast medium depends on its concentration and also the size of Bead Block® being used
Bead-Block-Contrast-Media-Chart21.png
(Click image to enlarge)


What catheter sizes can I use with Bead Block®?

Bead Block® is compatible with all 4F and 5F catheters (minimum ID of 0.040”/1040µm)

(Click image to enlarge)


How long will Bead Block® stay in the arteries?

Bead Block® and LC Bead® are made from identical materials and are both classified as permanent embolic agents.

No visible change to the LC Bead® product has been observed in histological analyses reported in three month intrahepatic implants in vivo*

  • 6 month subcutaneous implants in vivo**
  • 12 month intracerebral implants in vivo***
  • Therefore, Bead Block® is expected to perform in a similar manner to LC Bead®.
 * Lewis AL, et al, JVIR (2006): 17; 1335-1343
** NAmSA, report on file at Biocompatibles
*** Vinchon-Petit S, et al, Int J Pharmaceut (2010): 402: 184-9